CLSPN Polyclonal Antibody, 50ul Gene Synthesis This gene was initially mapped

This gene was initially mapped to chromosome 14

It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes

Cyclin dependent kinase 8 encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family

PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family| which belongs to the immunoglobulin superfamily

A second breast cancer susceptibility gene

CLSPN Polyclonal Antibody, 50ul Gene Synthesis This gene was initially mappedThe product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene.