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UBC12 Rabbit Polyclonal Antibody, 50ul Lentiviral Packaging Polymorphisms in this gene have

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UBC12 Rabbit Polyclonal Antibody, 50ul Lentiviral Packaging Polymorphisms in this gene haveThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes or E1s ubiquitin conjugating enzymes or E2s and ubiquitin protein ligases or E3s. This gene encodes a member of the E2 ubiquitin conjugating enzyme family. The encoded protein is linked with a ubiquitin like protein NEDD8

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Description

Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis

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Alternatively spliced transcript variants encoding different isoforms have been described for CNTROB

Catalytic activity:ATP + thymidine = ADP + thymidine 5'-phosphate

It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function

UBC12 Rabbit Polyclonal Antibody, 50ul Lentiviral Packaging Polymorphisms in this gene haveThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes or E1s ubiquitin conjugating enzymes or E2s and ubiquitin protein ligases or E3s. This gene encodes a member of the E2 ubiquitin conjugating enzyme family. The encoded protein is linked with a ubiquitin like protein NEDD8

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