PDK1 Polyclonal Antibody, 50ul[BT-AP07028] Electronic Pipette Allelic variants of this gene

Allelic variants of this gene have been associated with obesity

Alternative splicing results in four transcript variants encoding four distinct isoforms

The protein encoded by this gene is a member of serine/threonine protein kinase family

a cytosolic phosphoprotein implicated in tumorigenesis

An important paralog of this gene is RABEP2

PDK1 Polyclonal Antibody, 50ul[BT-AP07028] Electronic Pipette Allelic variants of this genePyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced