Tuberin Polyclonal Antibody, 100ul[BT-AP09287] Peptide Library An important paralog of this

An important paralog of this gene is LONP1

peripheral blood leukocyte

The extracellular portion of the protein interacts with fibroblast growth factors| setting in motion a cascade of downstream signals| ultimately influencing mitogenesis and differentiation

The gene is located in a head-to-head orientation with HARSL on chromosome five

The gene is expressed in most nonlymphoid human tissues including prostate

Tuberin Polyclonal Antibody, 100ul[BT-AP09287] Peptide Library An important paralog of thisMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.