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CD58 Polyclonal Antibody, 50ul[BT-AP02213] Apoptosis & Autophagy This gene is ubiquitously expressed

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CD58 Polyclonal Antibody, 50ul[BT-AP02213] Apoptosis & Autophagy This gene is ubiquitously expressedCREB1 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. Cyclic AMP responsive element binding protein 1 binds as a homodimer to the cAMP responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants

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Description

This gene is ubiquitously expressed

and is considered to be a plausible candidate gene for High Bone Mass Syndrome

Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion

Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size

PTGIS (prostaglandin I2 (prostacyclin) synthase) encodes a member of the cytochrome P450 superfamily of enzymes

CD58 Polyclonal Antibody, 50ul[BT-AP02213] Apoptosis & Autophagy This gene is ubiquitously expressedCREB1 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. Cyclic AMP responsive element binding protein 1 binds as a homodimer to the cAMP responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants

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