DSCR 1 Polyclonal Antibody, 100ul Enzymes Induction of apoptosis results in

Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation

The different subunits arise from alternative splicing in the 3' coding region

also known as Lon protease

The protein functions as a steroid-hormone activated transcription factor

Featuring a 0

DSCR 1 Polyclonal Antibody, 100ul Enzymes Induction of apoptosis results inRegulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of RCAN1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.