HUS1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation CCT8 encodes the theta subunit

CCT8 encodes the theta subunit of the CCT chaperonin

a tumor suppressor protein related to APC/beta-catenin signaling pathway

The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I

The protein can activate the complement pathway in association with MASPs and sMAP

It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein

HUS1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation CCT8 encodes the theta subunitThe protein encoded by this gene is a component of an evolutionarily conserved, genotoxin activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C