Dok-3 Polyclonal Antibody, 20ul Electrophoresis & Labeling These peptides act as autocrine

These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system

The product of this gene is localized to the plasma membrane

and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening

and certain facial and developmental defects

The protein encoded by KRT19 is a member of the keratin family

Dok-3 Polyclonal Antibody, 20ul Electrophoresis & Labeling These peptides act as autocrineDok 1, Dok 2 and Dok 3 are members of a class of "docking" proteins which contain multiple tyrosine residues and putative SH2 binding sites. Dok 1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Dok 2 (also designated p56 Dok) has also been identified as a potential mediator of the effects of p210 Bcr Abl. Dok 3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B