WFS1 Polyclonal Antibody, 50ul Roller Bottles This gene encodes a secreted

This gene encodes a secreted proprotein that is further processed into multiple mature peptides

Phosphorylation results in the inhibition of transcriptional coactivation through YWHAZ-mediated nuclear export

Mutations in this gene have been associated with congenital insensitivity to pain| anhidrosis| self-mutilating behavior| mental retardation and cancer

Related pseudogenes have been identified on chromosomes 4 and 14

This gene encodes a member of the taxilin family

WFS1 Polyclonal Antibody, 50ul Roller Bottles This gene encodes a secretedThis gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system.