DTL Polyclonal Antibody, 100ul Molecular Sciences Multiple transcript variants encoding at

Multiple transcript variants encoding at least two different isoforms have been found for this gene

This gene encodes a member of the peptidase T1A family| that is a 20S core alpha subunit

Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis

This receptor protein preferentially expresses in the thymus

Alternatively splice transcript variants encoding different isoforms have been found for this gene

DTL Polyclonal Antibody, 100ul Molecular Sciences Multiple transcript variants encoding atdevelopmental stage: Expressed in all fetal tissues examined, included brain, lung, liver, and kidney.,Required for CDT1 proteolysis in response to DNA damage through the CUL4 DDB1 E3 ubiquitin protein ligase. Seems to be necessary to ensure proper cell cycle regulation of DNA replication. May function as a substrate receptor for CUL4 DDB1 E3 ubiquitin protein ligase complex. May play a role in cell proliferation of NT2 embryonal carcinoma cells.,PTM: