Phospho-Bim (S59) Polyclonal Antibody, 20ul Cell Biology An alternatively spliced transcript variant
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Phospho-Bim (S59) Polyclonal Antibody, 20ul Cell Biology An alternatively spliced transcript variantBim Bod is a pro apoptotic protein belonging to the BH3 only group of Bcl 2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains. Bim induces apoptosis by binding to and antagonizing anti apoptotic members of the Bcl 2 family. Interactions have been observed with Bcl 2, Bcl xL, Mcl 1, Bcl w, Bfl 1, and BHRF 1. Bim functions in regulating apoptosis associated with thymocyte negative
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