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PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser Multiple alternatively spliced transcript variants

SKU: 68518268645

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PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser Multiple alternatively spliced transcript variantsProprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate

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Description

Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif

This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs

and it can interact with CT120

TCF4 encodes transcription factor 4

PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser Multiple alternatively spliced transcript variantsProprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate

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