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Rb(Phospho Ser788) Polyclonal Antibody, 100ul Contamination Detection & Removal Aladin encoded by AAAS is

SKU: 67902231953

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Rb(Phospho Ser788) Polyclonal Antibody, 100ul Contamination Detection & Removal Aladin encoded by AAAS isThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Aladin encoded by AAAS is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system

The product of GRK2 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations

Has no activity towards aliphatic aldehydes and ketones

CD71 is also found on most dividing cells and on brain endothelium

one appearing in S phase

Rb(Phospho Ser788) Polyclonal Antibody, 100ul Contamination Detection & Removal Aladin encoded by AAAS isThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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