VPS16 Rabbit Polyclonal Antibody, 50ul Cell Proliferation NTF3-deficient mice generated by gene

NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs

Mutations in this gene cause the syndrome of apparent mine

The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs

This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains

These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways

VPS16 Rabbit Polyclonal Antibody, 50ul Cell Proliferation NTF3-deficient mice generated by geneVesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes lysosomes and like their yeast counterparts