VPS35 Polyclonal Antibody, 100ul Isothermal Amplification Multiple cysteine residues are necessary

Multiple cysteine residues are necessary for proper targeting to the plasma membrane

where it functions as a negative regulator of cell growth and survival

Mutations in ACVR1B are associated with pituitary tumors

The other predicted transmembrane region is probably a hairpin-type region embedded into the membrane

Alternative splicing of RAB34 results in multiple transcript variants

VPS35 Polyclonal Antibody, 100ul Isothermal Amplification Multiple cysteine residues are necessaryVPS35 (VPS35, retromer complex component) belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and