Smad6 Polyclonal Antibody, 100ul DNA/RNA Isolation & Purification Promotes the exchange of GDP

Promotes the exchange of GDP to GTP

The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway

Down-regulated in brain tumors as compared to control brain tissues

Wiskott-Aldrich syndrome is a rare

The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine

Smad6 Polyclonal Antibody, 100ul DNA/RNA Isolation & Purification Promotes the exchange of GDPThe protein encoded by SMAD6 belongs to the SMAD family of proteins, which are related to Drosophila mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF beta activin signalling. Multiple transcript variants have been found for this gene.