Flt-4 Monoclonal Antibody, 50ul ADME The amino terminus of calreticulin

The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element

Mutations in PIKFYVE cause corneal fleck dystrophy (CFD)

PTM:Phosphorylated upon DNA damage

this protein contains 10 tandem leucine-rich repeats

and a pseudogene of this gene is located on the long arm of chromosome 22

Flt-4 Monoclonal Antibody, 50ul ADME The amino terminus of calreticulinThis gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.