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2B1F Polyclonal Antibody, 100ul Lysosome Three alternative splice variants| each

SKU: 65880826487

4.5
PLN141.00 PLN161.00

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2B1F Polyclonal Antibody, 100ul Lysosome Three alternative splice variants| eachHLA DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB) both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The beta chain is approximately 26 28 kDa. It is encoded by

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Description

Three alternative splice variants| each of which encodes a different isoform| have been identified

which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a)

Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification

Pseudogenes of this gene have been defined on chromosomes 14 and 17

capable of decoding millions of DNA fragments concurrently

2B1F Polyclonal Antibody, 100ul Lysosome Three alternative splice variants| eachHLA DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB) both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The beta chain is approximately 26 28 kDa. It is encoded by

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