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APLP-1 Polyclonal Antibody, 100ul Thermal Control The product of MED13 is

SKU: 64848674863

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APLP-1 Polyclonal Antibody, 100ul Thermal Control The product of MED13 isAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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Description

The product of MED13 is proposed to form a sub-complex with MED12

Alternatively spliced transcript variants encoding multiple isoforms have been observed for SLC9A3R2

Diseases associated with PRDM12 include neuropathy

An important paralog of this gene is HAP1

This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules

APLP-1 Polyclonal Antibody, 100ul Thermal Control The product of MED13 isAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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