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CHIP Polyclonal Antibody, 100ul Gene Synthesis Its expression is upregulated during

SKU: 64807002079

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CHIP Polyclonal Antibody, 100ul Gene Synthesis Its expression is upregulated duringThis gene encodes a protein containing tetratricopeptide repeat and a U box that functions as a ubiquitin ligase cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

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Description

Its expression is upregulated during dendritic cells maturation

CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina

Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2)

is approximately 16 kb away

which catalyze the reversible hydration of carbon dioxide in various biological processes

CHIP Polyclonal Antibody, 100ul Gene Synthesis Its expression is upregulated duringThis gene encodes a protein containing tetratricopeptide repeat and a U box that functions as a ubiquitin ligase cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

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