EGF Receptor(Phospho-Tyr1148) Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis The phosphorylation of this protein

The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex

May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage

CACNA1H encodes a T-type member of the alpha-1 subunit family

The encoded protein is found in a centrosomal complex with FEZ1

assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site

EGF Receptor(Phospho-Tyr1148) Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis The phosphorylation of this proteinThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.