RUNX1(Phospho Ser435) Polyclonal Antibody, 100ul Glassware It is very conserved in

It is very conserved in evolution

This gene is present in a cluster of related genes and pseudogenes on chromosome 12

Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome

The function of this protein has not been determined

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RUNX1(Phospho Ser435) Polyclonal Antibody, 100ul Glassware It is very conserved inCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have