Paxillin Polyclonal Antibody, 100ul[BT-AP06956] Cell Labeling & Imaging The homodimers and heterodimers compete

The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation

The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen

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The encoded protein may enhance cell proliferation

Mutations in LMNA lead to several diseases: emery-Dreifuss muscular dystrophy

Paxillin Polyclonal Antibody, 100ul[BT-AP06956] Cell Labeling & Imaging The homodimers and heterodimers competePXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.