FAK Monoclonal Antibody, 50ul[BT-MCA0528] Pipette Holder and mutations in DYRK1B were

and mutations in DYRK1B were found to cause abdominal obesity-metabolic syndrome 3

SYCP3 encodes an essential structural component of the synaptonemal complex

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ABHD12 encodes an enzyme (abhydrolase domain containing 12) that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG)

where it hydrolyzes stored triglycerides to free fatty acids

FAK Monoclonal Antibody, 50ul[BT-MCA0528] Pipette Holder and mutations in DYRK1B wereThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal