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IRAK-1 Polyclonal Antibody, 50ul[BT-AP04619] Adeno-associated Virus Packaging This gene encodes a transmembrane

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IRAK-1 Polyclonal Antibody, 50ul[BT-AP04619] Adeno-associated Virus Packaging This gene encodes a transmembraneIRAK1 encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family

CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation

This gene shares sequence similarity with mouse LLRep3

Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644

share a 5' non-coding exon

IRAK-1 Polyclonal Antibody, 50ul[BT-AP04619] Adeno-associated Virus Packaging This gene encodes a transmembraneIRAK1 encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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