NPBW2 Polyclonal Antibody, 20ul Cell Separation and Collection disease:Defects in GRN are the

disease:Defects in GRN are the cause of ubiquitin-positive frontotemporal dementia (UP-FTD)

The cAMP regulated phosphoprotein 21 is enriched in the caudate nucleus and cerebellar cortex

There are numerous pseudogenes of this gene distributed throughout the genome

Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain

including ankyrin-like repeats

NPBW2 Polyclonal Antibody, 20ul Cell Separation and Collection disease:Defects in GRN are theThe protein encoded by this gene is an integral membrane protein and G protein coupled receptor. The encoded protein is similar in sequence to another G protein coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain.