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SMCE1 Polyclonal Antibody, 100ul Antisense Oligonucleotides a novel anti-convulsant drug

SKU: 62738613963

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SMCE1 Polyclonal Antibody, 100ul Antisense Oligonucleotides a novel anti-convulsant drugThe protein encoded by this gene is part of the large ATP dependent chromatin remodeling complex SWI SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI SNF complex, can bind to 4 way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA binding HMG domain, but disruption of this domain

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Description

a novel anti-convulsant drug

Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3)

domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins

May play an important role in CNS diseases which involve T-cell recruitment

This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum

SMCE1 Polyclonal Antibody, 100ul Antisense Oligonucleotides a novel anti-convulsant drugThe protein encoded by this gene is part of the large ATP dependent chromatin remodeling complex SWI SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI SNF complex, can bind to 4 way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA binding HMG domain, but disruption of this domain

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