Integrin Alpha3 Polyclonal Antibody, 100ul[BT-AP04572] PCR Series up-regulates transcription from the osteocalcin

up-regulates transcription from the osteocalcin promoter

Activates the Arp2/3 complex to induce branched actin filament networks

and three alternative downstream AUG initiation codons

This member contains a nuclear targeting signal sequence

The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1

Integrin Alpha3 Polyclonal Antibody, 100ul[BT-AP04572] PCR Series up-regulates transcription from the osteocalcinITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia.