UPAR Rabbit Polyclonal Antibody, 20ul Live Cell Imaging Some members of this family

Some members of this family bind to DNA by zinc-mediated secondary structures called zinc fingers| and are involved in transcriptional regulation

The encoded protein has been shown to interact with the cancer developmental regulators SMAD2

and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD)

This protein localizes to the extracellular matrix

The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics

UPAR Rabbit Polyclonal Antibody, 20ul Live Cell Imaging Some members of this familyActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis independent signal transduction activation effects of U PA. It is subject to negative feedback regulation by U PA which cleaves it into an inactive form. Contains 3 UPAR Ly6 domains. subunit: Monomer (Probable). Interacts with MRC2.