PWWP2B Polyclonal Antibody, 50ul PCR Series In addition| this protein interacts

In addition| this protein interacts with BRCA1 and is phosphorylated by ATM| indicating a potential role for this protein in DNA repair

while maintaining suppression of p53 transactivation and apoptotic functions

The product of this gene belongs to a subfamily of calcium binding proteins

This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides

Depending on the binding site and binding partner

PWWP2B Polyclonal Antibody, 50ul PCR Series In addition| this protein interactsPWWP2B (PWWP domain containing 2B) is a 590 amino acid protein that contains a PWWP domain which is involved in protein protein interactions. The PWWP2B protein is phosphorylated upon DNA damage, probably by Atm or ATR. The PWWP2B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q26. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4. % of total DNA in cells and encodes