EphA10 Polyclonal Antibody, 50ul Mechanical Pipette The N-terminus of this protein

The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions

This gene is present in a gene cluster with other members of the ADAM family on chromosome 8

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins

|tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level)

Its expression is thought to be restricted to striated muscle

EphA10 Polyclonal Antibody, 50ul Mechanical Pipette The N-terminus of this proteinEphrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al. 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.