CD56 Polyclonal Antibody, 100ul[BT-AP02210] Recombinant Protein defects in IFNGR1 are a

defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease

Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)

The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies

and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis

The encoded hybrid proteins are likely responsible for transforming activity

CD56 Polyclonal Antibody, 100ul[BT-AP02210] Recombinant Protein defects in IFNGR1 are aCREB1 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. Cyclic AMP responsive element binding protein 1 binds as a homodimer to the cAMP responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants