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TNNC2 Polyclonal Antibody, 20ul Gene Editing Alternatively spliced transcript variants encoding

SKU: 61327476096

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TNNC2 Polyclonal Antibody, 20ul Gene Editing Alternatively spliced transcript variants encodingTroponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn I subunit inhibits actomyosin ATPase, the Tn T subunit binds tropomyosin and Tn C, while the Tn C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn C subunit.

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Description

Alternatively spliced transcript variants encoding the distinct isoforms have been described

This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet

The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor

This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum

however when expressed in cells alone or with other GABAB subunits

TNNC2 Polyclonal Antibody, 20ul Gene Editing Alternatively spliced transcript variants encodingTroponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn I subunit inhibits actomyosin ATPase, the Tn T subunit binds tropomyosin and Tn C, while the Tn C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn C subunit.

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