FAT10 Polyclonal Antibody, 50ul Proteases This intronless gene is deleted

This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome

It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors

and may be an important regulator of embryonic development

if not all cells

The elevated expression can be repressed by adenomatosis polyposis coli (APC)

FAT10 Polyclonal Antibody, 50ul Proteases This intronless gene is deletedFAT10, also designated Ubiquitin D or Diubiquitin, is a 165 amino acid protein encoded in the major histocompatibility complex (MHC) that consists of two domains which share significant homology with ubiquitin. Each domain contains two cysteines, along with a free C terminal diglycine motif required for FAT10 conjugate formation. FAT10 is inducible by interferon g and tumor necrosis factor a (TNF). The FAT10 protein interacts with MAD2, a component of