BIN3 Rabbit Polyclonal Antibody, 20ul Vortex Mixer the receptor associates with G-proteins

the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system

May play a role in the uptake and recycling of iron| via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme

Specifically phosphorylates 'Tyr-505' on LCK

TNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs

Gaucher disease

BIN3 Rabbit Polyclonal Antibody, 20ul Vortex Mixer the receptor associates with G-proteinsThe product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.