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Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2)

including the hexadecapeptide

|tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level)

DNA-dependent protein kinase

AXIN1 Polyclonal Antibody, 50ul Metabolic enzymes Upgrade your microplate mixer experienceThis gene encodes a cytoplasmic protein which contains a regulation of G protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta 1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The