RN139 Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos while its intracellular domain interacts
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RN139 Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos while its intracellular domain interactsThe protein encoded by this gene is a multi membrane spanning protein containing a RING H2 finger. This protein is located in the endoplasmic reticulum and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3: 8) translocation in a family with hereditary renal and non medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL
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