APEX2 Rabbit Polyclonal Antibody, 100ul Molecular Biology chromosome 10 makes up approximately

chromosome 10 makes up approximately 4

Enhances the transcriptional repressor activity of NR1D1 through stabilization of NR1D1 protein levels by preventing its ubiquitination and subsequent degradation (PubMed: 18235501

AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites

a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation

and 36 kDa

APEX2 Rabbit Polyclonal Antibody, 100ul Molecular Biology chromosome 10 makes up approximatelyApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II