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ING4 Polyclonal Antibody, 50ul PCR Series The encoded protein is a

SKU: 57454055298

4.4
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ING4 Polyclonal Antibody, 50ul PCR Series The encoded protein is aING4 encodes a tumor suppressor protein that contains a PHD finger, which is a common motif in proteins involved in chromatin remodeling. Inhibitor of growth protein 4 can bind TP53 and EP300 p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53 dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.

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Description

The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics

An important paralog of this gene is ZDHHC15

The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L)| which suggests the antiapoptotic function of this gene in cells

function:Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro)

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble

ING4 Polyclonal Antibody, 50ul PCR Series The encoded protein is aING4 encodes a tumor suppressor protein that contains a PHD finger, which is a common motif in proteins involved in chromatin remodeling. Inhibitor of growth protein 4 can bind TP53 and EP300 p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53 dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.

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