RBM3 Rabbit Polyclonal Antibody, 100ul Mechanical Pipette Mutations in this gene may

Mutations in this gene may lead to cryptorchidism

The encoded protein plays a role in the inducible expression of cytokine genes in T cells| especially in the induction of interleukin-2 and interleukin-4

Two transcript variants encoding different isoforms have been found for CDC25A

resulting in the inhibition of TRAF6 NF-kappa-B activation

The protein encoded by this gene is localized exclusively in the cell nucleus

RBM3 Rabbit Polyclonal Antibody, 100ul Mechanical Pipette Mutations in this gene mayThis gene is a member of the glycine rich RNA binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense mediated decay (NMD) criteria.