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MAD1 Polyclonal Antibody, 100ul Buffers & Solutions binds directly to the DNA

SKU: 57129861131

4.8
USD141.00 USD177.00

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MAD1 Polyclonal Antibody, 100ul Buffers & Solutions binds directly to the DNAMAD1L1 (MAD1 mitotic arrest deficient like 1) is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.

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Description

binds directly to the DNA substrates and cooperates with the Ku70/G22P1-Ku80/XRCC5 (Ku) dimer to establish a functional preligation complex

Attenuates TNF-mediated endothelial expression of leukocyte adhesion molecules

kinin generation and inflammation

The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG

member 5 (IL1F5/IL-1 delta)

MAD1 Polyclonal Antibody, 100ul Buffers & Solutions binds directly to the DNAMAD1L1 (MAD1 mitotic arrest deficient like 1) is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.

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