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Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription The encoded protein has been

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Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription The encoded protein has beenBim Bod is a pro apoptotic protein belonging to the BH3 only group of Bcl 2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains. Bim induces apoptosis by binding to and antagonizing anti apoptotic members of the Bcl 2 family. Interactions have been observed with Bcl 2, Bcl xL, Mcl 1, Bcl w, Bfl 1, and BHRF 1. Bim functions in regulating apoptosis associated with thymocyte negative

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Description

The encoded protein has been shown to interact with NM23-2

a group of proteins found associated with NMDA receptors at synapses

CREB3 (cAMP responsive element binding protein 3) encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins

This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but

The protein contains a putative src homology 2 (SH2) domain

Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription The encoded protein has beenBim Bod is a pro apoptotic protein belonging to the BH3 only group of Bcl 2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains. Bim induces apoptosis by binding to and antagonizing anti apoptotic members of the Bcl 2 family. Interactions have been observed with Bcl 2, Bcl xL, Mcl 1, Bcl w, Bfl 1, and BHRF 1. Bim functions in regulating apoptosis associated with thymocyte negative

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