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Rho H Polyclonal Antibody, 100ul Yeast Expression It exists as two isoenzymes

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Rho H Polyclonal Antibody, 100ul Yeast Expression It exists as two isoenzymesThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non Hodgkin's lymphoma occur between this locus and B cell CLL lymphoma 6 (BCL6) on chromosome 3, leading to

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Description

It exists as two isoenzymes

which are postulated to function in lipid synthesis

It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS

Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region

Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2

Rho H Polyclonal Antibody, 100ul Yeast Expression It exists as two isoenzymesThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non Hodgkin's lymphoma occur between this locus and B cell CLL lymphoma 6 (BCL6) on chromosome 3, leading to

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