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Tau(Phospho Thr212) Polyclonal Antibody, 100ul Microplate Mixer Variation in this gene is

SKU: 53776240135

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Tau(Phospho Thr212) Polyclonal Antibody, 100ul Microplate Mixer Variation in this gene isThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,

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Description

Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations

This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls

This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum

which catalyzes the removal of the 3' trailer from precursor tRNAs

This protein also functions as a co-activator of the transcriptional activator p63

Tau(Phospho Thr212) Polyclonal Antibody, 100ul Microplate Mixer Variation in this gene isThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,

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