Phospho-AIP4 (Y420) Polyclonal Antibody, 20ul Protein Research Mutations in MYOZ2 cause cardiomyopathy
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Phospho-AIP4 (Y420) Polyclonal Antibody, 20ul Protein Research Mutations in MYOZ2 cause cardiomyopathyITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations
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