Pim-1 Polyclonal Antibody, 20ul Pathway and Network Analysis Knockout studies in mice suggest

Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis

Two transcript variants encoding different isoforms have been found for CA2

Mutations in this gene are associated with glycerol kinase deficiency (GKD)

NXF3 (nuclear RNA export factor 3) is one member of a family of nuclear RNA export factor genes

Pim-1 Polyclonal Antibody, 20ul Pathway and Network Analysis Knockout studies in mice suggestThe protein encoded by PIM1 (Pim 1 proto oncogene, serine threonine kinase) belongs to the Ser Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both