Paxillin Polyclonal Antibody, 50ul[BT-AP06957] Serological Pipets Plays a role in the

Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton

It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle

The encoded protein associates with HDL

More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases

Belongs to the rad9 family

Paxillin Polyclonal Antibody, 50ul[BT-AP06957] Serological Pipets Plays a role in thePXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.