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DHX58 Polyclonal Antibody, 50ul Cellular Function Assays In rat| this protein localizes

SKU: 52383829241

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DHX58 Polyclonal Antibody, 50ul Cellular Function Assays In rat| this protein localizesNegative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58 mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP binding domain.,Contains 1 helicase C terminal domain.,subunit: Interacts with DDX58 and probably blocks its homomultimerization.,

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Description

In rat| this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal

It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling

VWA5A (von Willebrand factor A domain containing 5A)

The protein encoded by CEBPE is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions

alternatively spliced form

DHX58 Polyclonal Antibody, 50ul Cellular Function Assays In rat| this protein localizesNegative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58 mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP binding domain.,Contains 1 helicase C terminal domain.,subunit: Interacts with DDX58 and probably blocks its homomultimerization.,

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