CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays A similar protein in rat

A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family

suggesting that it may be involved in extracellular matrix adhesion

secreted protein containing a C-terminal fibrinogen domain

Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder

Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED)

CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays A similar protein in ratThis gene is encodes a cytoplasmic protein with three cytoskeletal associated protein glycine conserved (CAP GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis multiple familial trichoepithelioma and Brooke Spiegler syndrome. Alternate transcriptional splice variants encoding different isoforms have been characterized.