HACE1 Polyclonal Antibody, 20ul Vector Construction Interacts with RXRA

Interacts with RXRA

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implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression

Mutations in this gene are associated with two types of recessive osteochondrodysplasia| Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia| which involve both skeletal defects and mental retardation

and it may be involved in the regulation of specific developmental processes in the CNS

HACE1 Polyclonal Antibody, 20ul Vector Construction Interacts with RXRAThis gene encodes a HECT domain and ankyrin repeat containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor.